Leaky Gut Syndromes: Breaking the Vicious Cycle

...From the perspective of function, the contents of the gut lumen lie outside the body and contain a toxic/antigenic load from which the body needs to be protected.

Protection is supplied by complex mechanisms which support one another: intestinal secretions (primarily mucus and secretory IgA), the mucosal epithelium, and intramural lymphocytes........

......Leaky Gut Syndromes are clinical disorders associated with increased intestinal permeability.

They include inflammatory and infectious bowel diseases, chronic inflammatory arthritides, cryptogenic skin conditions like acne, psoriasis and dermatitis herpetiformis, many diseases triggered by food allergy or specific food intolerance, including eczema, urticaria, and irritable bowel syndrome, AIDS, chronic fatigue syndromes, chronic hepatitis, chronic pancreatitis.......

...Leaky Gut Syndromes are usually provoked by exposure to substances which damage the integrity of the intestinal mucosa, disrupting the desmosomes which bind epithelial cells and increasing passive, para-cellular absorption.

The commonest causes of damage are infectious agents (viral, bacterial and protozoan).....

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